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Cancer Therapy Pathways and Regimens

Detailed, evidence-based regimens for providers in cancer care. Health care professionals, learn how you can participate in the Cancer Therapy Pathways Program today.

Health care professionals can help enhance quality and value in cancer care through our Cancer Therapy Pathways and Regimens. Cancer Therapy Pathways and Regimens are detailed, evidence-based regimens associated with better clinical outcomes that we’ve selected through rigorous evaluation for specific cancer types and states.

The pathways

Review the full list of the Cancer Therapy Pathways and Regimens 

Interactive guide

Access our self-paced guide for everything you need to know about Cancer Therapy Pathways and Regimens

Select a Preferred Pathways Regimens

Select the Cancer Therapy Pathways and Regimens, if appropriate, and track your progress in the Optum Cancer Guidance Program tool. 

Eligibility

Submit your prior authorization requests for chemotherapy or related therapies through the CGP tool for patients who are UnitedHealthcare Community Plan, Medicare Advantage or commercial plan members. Providers in all states are eligible to use our Cancer Therapy Pathways and Regimens.

Note: Pathway selection isn't required to receive prior authorization approval for therapy.

How we develop the pathways

Strong basis


We use a comprehensive literature review of all National Comprehensive Cancer Network (NCCN)-recommended regimens.

Careful selection


We select regimens by efficacy, safety/toxicity and medication drug cost, which we only review when efficacy and safety between regimens are comparable. We also use our member data to better understand the typical duration of therapy, hospitalization rates and total cost of care.

Expert evaluation


The UnitedHealthcare Oncology Advisory Committee and disease-specific expert consultants review and evaluate each therapy pathway. We select the members of this committee for their clinical expertise and diverse perspectives. The committee includes practicing medical oncologists from academic medical centers and community oncology practices.